Global Health Research

Malaria Intervention Modeling Project

Optimizing Chemoprevention and Vaccine Strategies in High-Burden African Countries

2024-2027
WHO-Aligned
Multi-Country
2024-2027
Duration
High-Burden African Nations
Focus Countries
Children Under 5
Target Population
90% Malaria Reduction
Goal
Malaria prevention strategies

Malaria Prevention Strategies

Evaluating the impact of chemoprevention and vaccines across Africa

Community health workers

Community Health Workers

Training healthcare providers in malaria prevention techniques

Malaria vaccination

Vaccination Programs

Implementing WHO-approved malaria vaccines in high-burden regions

Research collaboration

Research Collaboration

African scientists working together to model malaria intervention strategies

Child health protection

Child Health Protection

Focusing on interventions for children under five who are most vulnerable

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Addressing Africa's Malaria Burden

Malaria remains one of Africa's most devastating public health challenges, with the continent bearing over 90% of global malaria deaths. Children under five are particularly vulnerable, accounting for approximately 80% of all malaria mortality in Africa.

Our project focuses on modeling the health impact and cost-effectiveness of combining malaria chemoprevention strategies with the new generation of malaria vaccines to optimize intervention approaches in high-burden settings.

The Malaria Challenge: Key Facts

249 million malaria cases globally in 2022
608,000 malaria deaths in 2022 (90% in Africa)
1.2 billion cases prevented 2004-2019
Children under 5 account for 80% of deaths
Nigeria, DRC, Uganda, Mozambique bear highest burden

Project Rationale

Bridging the Implementation Gap

Current Challenges

  • • Global Technical Strategy for Malaria 2016–2030 is 44% off-track
  • • Projected 88% deviation from targets by 2030
  • • Limited evidence for optimal intervention combinations
  • • Implementation barriers in high-burden countries

Our Approach

  • • Comprehensive modeling of intervention strategies
  • • Cost-effectiveness analysis for decision-making
  • • Capacity building for African researchers
  • • Policy translation for implementation